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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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API CSV20행 · 1개 프로그램

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항목
AntibodystalePhase 2
177Lu-PNT2002 (177Lu-PNT2002)
Lantheus Medical Imaging·Metastatic Renal Cell Carcinoma
ORR 32%
Overview
Program
177Lu-PNT2002
Overview
Company
Lantheus Medical Imaging
Overview
Modality
ANTIBODY
Overview
Target
Metastatic Renal Cell Carcinoma
Overview
Indication
Metastatic Renal Cell Carcinoma; Metastatic Clear Cell Renal Cell Carcinoma
Overview
Phase
PHASE_2
Overview
Status
DISCONTINUED
PK/PD
Species
Human
PK/PD
Animal (cat.)
Human
PK/PD
Experiment
Secondary endpoints are radiographic and prostate-specific antigen-based progression, acute and late physician-scored toxicity, patient-reported quality of life, ADT-free survival, time to progression, overall survival, locoregional control, and duration of response.
Toxicology
Species
Human
Toxicology
Animal (cat.)
Human
Toxicology
Major finding
LUNAR: a randomized Phase 2 study of 177 Lutetium-PSMA Neoadjuvant to Ablative Radiotherapy for Oligorecurrent Prostate Cancer (clinical trial protocol).. To assess the efficacy of 177 Lu-PNT2002, a novel radiolabelled small molecule that binds with high affinity to prostate-specific membrane antigen (PSMA), in combination with stereotactic body radiotherapy (SBRT) to all sites of metastasis, vs S…
Clinical
Primary efficacy
ORR 32%
Clinical
ORR
30.1%
Clinical
PFS
9.5
Clinical
Result source
ClinicalTrials.gov NCT04647526
Clinical
Data Tier / Score
A · 10
Clinical
Program phase
PHASE_2
Clinical
Clinical sync
2026년 6월 1일 (43일 전 · 갱신 권장)