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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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API CSV20행 · 1개 프로그램

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항목
AntibodyPhase 2
18F-FLT (18F-FLT)
Angiochem Inc·Breast Cancer
ORR 71%
Overview
Program
18F-FLT
Overview
Company
Angiochem Inc
Overview
Modality
ANTIBODY
Overview
Target
Breast Cancer
Overview
Indication
Breast Cancer; Brain Metastases
Overview
Phase
PHASE_2
Overview
Status
ACTIVE
MoA
Biomarker
Biomarker of Tumor Cell Proliferation, Detected Differential Response to Various Cyclin-Dependent Kinase (CDK
PK/PD
Species
Mouse, Rat
PK/PD
Animal (cat.)
Mouse, Rat, In vitro
PK/PD
Experiment
Pharmacodynamic
Toxicology
Species
Mouse, Rat
Toxicology
Animal (cat.)
Mouse, Rat, In vitro
Toxicology
Major finding
FLT PET/CT imaging of metastatic prostate cancer patients treated with pTVG-HP DNA vaccine and pembrolizumab.. Immunotherapy has demonstrated remarkable success in treating different cancers. Nonetheless, a large number of patients do not respond, many respond without immediate changes detectable with conventional imaging, and many have unusual immune-related adverse events that cannot be predicte…
Clinical
Primary efficacy
ORR 71%
Clinical
ORR
71%
Clinical
Result source
ClinicalTrials.gov NCT01621906
Clinical
Data Tier / Score
A · 55
Clinical
Program phase
PHASE_2
Clinical
Clinical sync
2026년 7월 13일 (1일 전)