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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
CGTPhase 2
gene therapy (ADV/HSV-tk, ADV/HSV-tk (gene therapy))
The Methodist Hospital Research In…·Glioblastoma
42 trials
Overview
Program
ADV/HSV-tk (gene therapy)
Overview
Company
The Methodist Hospital Research Institute
Overview
Modality
CGT
Overview
Target
Glioblastoma
Overview
Indication
Glioblastoma; Anaplastic Astrocytoma
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
MoA
Mechanism
targeted chimeric antigen receptor
MoA
Biomarker
biomarkers in PCa patients undergoing hormonal therapy
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
Pd
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
Antimetabolites synergize with non-genotoxic antibody drug conjugate conditioning in hematopoietic stem cell lentiviral gene therapy.. Hematopoietic stem cell transplantation (HSCT) of genetically engineered cells is a promising treatment modality for monogenic diseases. However, hematopoietic stem cell (HSC)-directed lentiviral vector (LV) gene therapies remain limited by genotoxicities associate…
Clinical
PFS
1
Clinical
OS
2
Clinical
Result source
ClinicalTrials.gov NCT04406272
Clinical
Data Tier / Score
A · 42
Clinical
Program phase
PHASE_2
Clinical
Clinical sync
2026년 7월 13일 (1일 전)