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항목
AntibodyPreclinical
ADT (androgen deprivation therapy, androgen deprivation therapy (ADT))
Istituto Clinico Humanitas·Oligorecurrent and Oligoprogressiv…
72 trials
Overview
Program
androgen deprivation therapy (ADT)
Overview
Company
Istituto Clinico Humanitas
Overview
Modality
ANTIBODY
Overview
Target
Oligorecurrent and Oligoprogressive Pros
Overview
Indication
Oligorecurrent and Oligoprogressive Prostate Cancer Patients
Overview
Phase
PRECLINICAL
Overview
Status
RECRUITING
MoA
Mechanism
targeting Vβ6 and Vβ10 T-cell receptor
MoA
Biomarker
biomarker-driven studies in larger cohorts to refine treatment strategies
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
pd
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
SBRT plus abiraterone acetate and ADT versus abiraterone acetate and ADT in oligometastatic castrate-resistant prostate cancer (ARTO): long-term, unplanned overall survival analysis of an open-label, randomised, phase 2 trial.. The ARTO trial showed improved early clinical outcomes by adding metastasis-directed therapy (MDT), through stereotactic body radiotherapy (SBRT), to abiraterone acetate an…
Clinical
PFS
0
Clinical
Result source
ClinicalTrials.gov NCT01531205
Clinical
Data Tier / Score
A · 29
Clinical
Program phase
PRECLINICAL
Clinical
Clinical sync
2026년 7월 12일 (2일 전)