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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
CGTPhase 1
CART123 (Anti-CD123 LV redirected T cells, Anti-CD123 LV redirected T cells (CART123))
Stephan Grupp MD PhD·Acute Myeloid Leukemia (AML)
8 trials
Overview
Program
Anti-CD123 LV redirected T cells (CART123)
Overview
Company
Stephan Grupp MD PhD
Overview
Modality
CGT
Overview
Target
Acute Myeloid Leukemia (AML)
Overview
Indication
Acute Myeloid Leukemia (AML)
Overview
Phase
PHASE_1
Overview
Status
RECRUITING
MoA
Mechanism
targeted chimeric antigen receptor
MoA
Biomarker
CD19 and contains a high
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
CD123-targeted CAR T cell (CART123) is promising immunotherapy, but how to improve the complete remission (CR) rate and rescue potential hematopoietic toxicity still need to explore.
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
Donor-Derived CD123-Targeted CAR T Cell Serves as a RIC Regimen for Haploidentical Transplantation in a Patient With FUS-ERG + AML.. Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) following chemotherapy is part of standard treatment protocol for patients with acute myeloid leukemia (AML). FUS-ERG + AML is rare but has an extremely poor prognosis even with allo-HSCT in r…
Clinical
Data Tier / Score
A · 20
Clinical
Program phase
PHASE_1
Clinical
Clinical sync
2026년 7월 13일 (1일 전)