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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
AntibodyPhase 2
APG-157 (APG-157)
Aveta Biomics, Inc.·Glioma
5 trials
Overview
Program
APG-157
Overview
Company
Aveta Biomics, Inc.
Overview
Modality
ANTIBODY
Overview
Target
Glioma
Overview
Indication
Glioma; Glioblastoma Multiforme
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
MoA
Mechanism
targeting multiple pathway
MoA
Biomarker
Biomarker for Response to Therapy in Head & Neck Cancer
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
A randomized, phase 1, placebo-controlled trial of APG-157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor-associated microbes.. Although curcumin's effect on head and neck cancer has been studied in vitro and in vivo, to the authors' knowledge its efficacy is limited by poor systemic absorption from oral administration. APG-157 is a botanical drug c…
Clinical
Data Tier / Score
A · 14
Clinical
Program phase
PHASE_2
Clinical
Clinical sync
2026년 7월 13일 (1일 전)