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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
ADCPhase 2
Asparaginase Erwinia chrysanthemi (Asparaginase Erwinia chrysanthemi)
medac GmbH·Acute Myeloid Leukemia
42 trials
Overview
Program
Asparaginase Erwinia chrysanthemi
Overview
Company
medac GmbH
Overview
Modality
ADC
Overview
Target
Acute Myeloid Leukemia
Overview
Indication
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; T Acute Lymphoblastic Leukemia
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
MoA
Mechanism
(hydrolysis of circulating asparagine) and are associated with similar efficacy and toxicity patterns
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
Pharmacokinetic
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
Back to the future: the amazing journey of the therapeutic anti-leukemia enzyme asparaginase Erwinia chrysanthemi .. For several decades, asparaginase has been considered world-wide as an essential component of combination chemotherapy for the treatment of childhood acute lymphoblastic leukemia (ALL). Discovered over 60 years ago, two main unmanipulated asparaginase products originated from primar…
Clinical
OS
1.97
Clinical
Result source
ClinicalTrials.gov NCT04326439
Clinical
Data Tier / Score
A · 37
Clinical
Program phase
PHASE_2
Clinical
Clinical sync
2026년 7월 12일 (1일 전)