검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Azacytidine |
Overview Company | M.D. Anderson Cancer Center |
Overview Modality | ANTIBODY |
Overview Target | Hodgkin's Lymphoma |
Overview Indication | Hodgkin's Lymphoma |
Overview Phase | PHASE_2 |
Overview Status | RECRUITING |
MoA Mechanism | CAR T cells sustained high levels of interferon-γ production, which induced immunogenic cell death in tumor cells and activated conventional dendritic cell |
MoA Biomarker | biomarker, we constructed PPI networks and applied three ML methods: least absolute shrinkage and selection o |
PK/PD Species | Mouse, Rat |
PK/PD Animal (cat.) | Mouse, Rat |
PK/PD Experiment | PD |
Toxicology Species | Mouse, Rat |
Toxicology Animal (cat.) | Mouse, Rat |
Toxicology Major finding | Dnmt1 associated Gja1 promoter methylation changes are implicated in Cx43 remodeling during acute myocardial ischemia/reperfusion injury.. DNA methylation has traditionally been regarded as a stable epigenetic modification. However, emerging evidence indicates that oxidative and genotoxic stress can induce locus-specific methylation changes that modulate transcriptional responses. The contribution… |
Clinical Primary efficacy | ORR 48% |
Clinical ORR | 48% |
Clinical OS | 62 |
Clinical Result source | ClinicalTrials.gov NCT00660400 |
Clinical Data Tier / Score | A · 53 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 13일 (1일 전) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Azacytidine |
Overview Company | M.D. Anderson Cancer Center |
Overview Modality | ANTIBODY |
Overview Target | Hodgkin's Lymphoma |
Overview Indication | Hodgkin's Lymphoma |
Overview Phase | PHASE_2 |
Overview Status | RECRUITING |
MoA Mechanism | CAR T cells sustained high levels of interferon-γ production, which induced immunogenic cell death in tumor cells and activated conventional dendritic cell |
MoA Biomarker | biomarker, we constructed PPI networks and applied three ML methods: least absolute shrinkage and selection o |
PK/PD Species | Mouse, Rat |
PK/PD Animal (cat.) | Mouse, Rat |
PK/PD Experiment | PD |
Toxicology Species | Mouse, Rat |
Toxicology Animal (cat.) | Mouse, Rat |
Toxicology Major finding | Dnmt1 associated Gja1 promoter methylation changes are implicated in Cx43 remodeling during acute myocardial ischemia/reperfusion injury.. DNA methylation has traditionally been regarded as a stable epigenetic modification. However, emerging evidence indicates that oxidative and genotoxic stress can induce locus-specific methylation changes that modulate transcriptional responses. The contribution… |
Clinical Primary efficacy | ORR 48% |
Clinical ORR | 48% |
Clinical OS | 62 |
Clinical Result source | ClinicalTrials.gov NCT00660400 |
Clinical Data Tier / Score | A · 53 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 13일 (1일 전) |
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