검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Bexarotene (Bexarotene) Millennium Pharmaceuticals, Inc.·Primary Cutaneous Anaplastic Large… ORR 54.7%·t½ 7 h |
|---|---|
Overview Program | Bexarotene |
Overview Company | Millennium Pharmaceuticals, Inc. |
Overview Modality | ADC |
Overview Target | Primary Cutaneous Anaplastic Large Cell |
Overview Indication | Primary Cutaneous Anaplastic Large Cell Lymphoma; Mycosis Fungoides |
Overview Phase | PHASE_3 |
Overview Status | ACTIVE |
MoA Mechanism | targeted interventions and supports APOE-associated pathway |
MoA Biomarker | biomarker, and proposes novel therapeutic strategies integrating machine learning and deep learning approache |
PK/PD Half-life | 7 h |
PK/PD Species | Mouse |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | pd |
Toxicology Species | Mouse |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | Vitamins and the skin: Vitamin A and retinoids in dermatology.. Vitamin A and analogs are widely used in dermatology, with retinoids being natural and synthetic vitamin A derivatives. Topical retinoids (especially tretinoin and tretinoin precursors) can diminish photoaging and contribute to the thickening and restoration of skin collagen. Retinoids used as therapeutic agents include oral retinoids… |
Clinical Primary efficacy | ORR 54.7% |
Clinical ORR | 54.7% |
Clinical Result source | ClinicalTrials.gov NCT01578499 |
Clinical Data Tier / Score | A · 56 |
Clinical Program phase | PHASE_3 |
Clinical Clinical sync | 2026년 7월 13일 (1일 전) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Bexarotene (Bexarotene) Millennium Pharmaceuticals, Inc.·Primary Cutaneous Anaplastic Large… ORR 54.7%·t½ 7 h |
|---|---|
Overview Program | Bexarotene |
Overview Company | Millennium Pharmaceuticals, Inc. |
Overview Modality | ADC |
Overview Target | Primary Cutaneous Anaplastic Large Cell |
Overview Indication | Primary Cutaneous Anaplastic Large Cell Lymphoma; Mycosis Fungoides |
Overview Phase | PHASE_3 |
Overview Status | ACTIVE |
MoA Mechanism | targeted interventions and supports APOE-associated pathway |
MoA Biomarker | biomarker, and proposes novel therapeutic strategies integrating machine learning and deep learning approache |
PK/PD Half-life | 7 h |
PK/PD Species | Mouse |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | pd |
Toxicology Species | Mouse |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | Vitamins and the skin: Vitamin A and retinoids in dermatology.. Vitamin A and analogs are widely used in dermatology, with retinoids being natural and synthetic vitamin A derivatives. Topical retinoids (especially tretinoin and tretinoin precursors) can diminish photoaging and contribute to the thickening and restoration of skin collagen. Retinoids used as therapeutic agents include oral retinoids… |
Clinical Primary efficacy | ORR 54.7% |
Clinical ORR | 54.7% |
Clinical Result source | ClinicalTrials.gov NCT01578499 |
Clinical Data Tier / Score | A · 56 |
Clinical Program phase | PHASE_3 |
Clinical Clinical sync | 2026년 7월 13일 (1일 전) |
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