검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Budigalimab |
Overview Company | AbbVie |
Overview Modality | ANTIBODY |
Overview Target | Hepatocellular Carcinoma |
Overview Indication | Hepatocellular Carcinoma |
Overview Phase | PHASE_3 |
Overview Status | RECRUITING |
MoA Mechanism | targets the costimulatory receptor |
MoA Biomarker | biomarker analyses were performed |
PK/PD Species | Mouse, Study objectives included safety, tolerability, pharmacokinetics, and preliminary antitumor activity. |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Mouse, Study objectives included safety, tolerability, pharmacokinetics, and preliminary antitumor activity. |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | Phase 1b study of ABBV-368, tilsotolimod, budigalimab, and nab-paclitaxel in patients with recurrent/metastatic head and neck squamous cell carcinoma.. ABBV-368 is a humanized monoclonal antibody that targets the costimulatory receptor OX40. Here, we investigate a treatment strategy with ABBV-368 combined with the investigational toll-like receptor 9 agonist tilsotolimod, the programmed cell death… |
Clinical Primary efficacy | ORR 14.3% |
Clinical ORR | 14.3% |
Clinical PFS | 5 |
Clinical OS | 0 |
Clinical Result source | ClinicalTrials.gov NCT04306900 |
Clinical Data Tier / Score | A · 52 |
Clinical Program phase | PHASE_3 |
Clinical Clinical sync | 2026년 7월 13일 (1일 전) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Budigalimab |
Overview Company | AbbVie |
Overview Modality | ANTIBODY |
Overview Target | Hepatocellular Carcinoma |
Overview Indication | Hepatocellular Carcinoma |
Overview Phase | PHASE_3 |
Overview Status | RECRUITING |
MoA Mechanism | targets the costimulatory receptor |
MoA Biomarker | biomarker analyses were performed |
PK/PD Species | Mouse, Study objectives included safety, tolerability, pharmacokinetics, and preliminary antitumor activity. |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Mouse, Study objectives included safety, tolerability, pharmacokinetics, and preliminary antitumor activity. |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | Phase 1b study of ABBV-368, tilsotolimod, budigalimab, and nab-paclitaxel in patients with recurrent/metastatic head and neck squamous cell carcinoma.. ABBV-368 is a humanized monoclonal antibody that targets the costimulatory receptor OX40. Here, we investigate a treatment strategy with ABBV-368 combined with the investigational toll-like receptor 9 agonist tilsotolimod, the programmed cell death… |
Clinical Primary efficacy | ORR 14.3% |
Clinical ORR | 14.3% |
Clinical PFS | 5 |
Clinical OS | 0 |
Clinical Result source | ClinicalTrials.gov NCT04306900 |
Clinical Data Tier / Score | A · 52 |
Clinical Program phase | PHASE_3 |
Clinical Clinical sync | 2026년 7월 13일 (1일 전) |
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