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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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API CSV21행 · 1개 프로그램

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항목
CGTPreclinical
CAR-GPC3 T Cells (CAR-GPC3 T Cells)
CARsgen Therapeutics Co., Ltd.·Hepatocellular Carcinoma
ORR 50%
Overview
Program
CAR-GPC3 T Cells
Overview
Company
CARsgen Therapeutics Co., Ltd.
Overview
Modality
CGT
Overview
Target
Hepatocellular Carcinoma
Overview
Indication
Hepatocellular Carcinoma
Overview
Phase
PRECLINICAL
Overview
Status
ACTIVE
MoA
Biomarker
biomarkers for chimeric antigen receptor-glypican-3 T-cell therapy in patients with hepatocellular carcinoma
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
PK
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
Chimeric Antigen Receptor-Glypican-3 T-Cell Therapy for Advanced Hepatocellular Carcinoma: Results of Phase I Trials.. Our preclinical studies demonstrated the potential of chimeric antigen receptor (CAR)-glypican-3 (GPC3) T-cell therapy for hepatocellular carcinoma (HCC). We report herein the first published results of CAR-GPC3 T-cell therapy for HCC. In two prospective phase I studies, adult pat…
Toxicology
CRS
grade 1
Clinical
Primary efficacy
ORR 50%
Clinical
ORR
50.0%
Clinical
Result source
ClinicalTrials.gov NCT04377932
Clinical
Data Tier / Score
A · 37
Clinical
Program phase
PRECLINICAL
Clinical
Clinical sync
2026년 7월 13일 (1일 전)