검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | CDX-3379 and cetuximab (CDX-3379 and cetuximab) Eli Lilly / Merck KGaA·Advanced Head and Neck Squamous Ce… ORR 7% |
|---|---|
Overview Program | CDX-3379 and cetuximab |
Overview Company | Eli Lilly / Merck KGaA |
Overview Modality | ANTIBODY |
Overview Target | Advanced Head and Neck Squamous Cell Car |
Overview Indication | Advanced Head and Neck Squamous Cell Carcinoma |
Overview Phase | PHASE_2 |
Overview Status | DISCONTINUED |
Toxicology Major finding | Molecular and Clinical Activity of CDX-3379, an Anti-ErbB3 Monoclonal Antibody, in Head and Neck Squamous Cell Carcinoma Patients.. ErbB3 and its ligand neuregulin-1 (NRG1) are widely expressed in head and neck squamous cell carcinoma (HNSCC) and associated with tumor progression. A "window-of-opportunity" study (NCT02473731) was conducted to evaluate the pharmacodynamic effects of CDX-3379, an an… |
Clinical Primary efficacy | ORR 7% |
Clinical ORR | 7% |
Clinical Result source | ClinicalTrials.gov NCT03254927 |
Clinical Data Tier / Score | A · 0 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 5월 22일 (53일 전 · 갱신 권장) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | CDX-3379 and cetuximab (CDX-3379 and cetuximab) Eli Lilly / Merck KGaA·Advanced Head and Neck Squamous Ce… ORR 7% |
|---|---|
Overview Program | CDX-3379 and cetuximab |
Overview Company | Eli Lilly / Merck KGaA |
Overview Modality | ANTIBODY |
Overview Target | Advanced Head and Neck Squamous Cell Car |
Overview Indication | Advanced Head and Neck Squamous Cell Carcinoma |
Overview Phase | PHASE_2 |
Overview Status | DISCONTINUED |
Toxicology Major finding | Molecular and Clinical Activity of CDX-3379, an Anti-ErbB3 Monoclonal Antibody, in Head and Neck Squamous Cell Carcinoma Patients.. ErbB3 and its ligand neuregulin-1 (NRG1) are widely expressed in head and neck squamous cell carcinoma (HNSCC) and associated with tumor progression. A "window-of-opportunity" study (NCT02473731) was conducted to evaluate the pharmacodynamic effects of CDX-3379, an an… |
Clinical Primary efficacy | ORR 7% |
Clinical ORR | 7% |
Clinical Result source | ClinicalTrials.gov NCT03254927 |
Clinical Data Tier / Score | A · 0 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 5월 22일 (53일 전 · 갱신 권장) |
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