검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-14 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Cyclophosphamid |
Overview Company | Essen Biotech |
Overview Modality | ANTIBODY |
Overview Target | Stomach Cancer |
Overview Indication | Stomach Cancer; Stomach Cancer Recurrent |
Overview Phase | PHASE_2 |
Overview Status | RECRUITING |
MoA Mechanism | CAR-T therapy induced profound, durable responses in extremely severe patients with seropositive PIRR |
MoA Biomarker | biomarkers |
PK/PD Species | Mouse, = , 0. |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | PK |
Toxicology Species | Mouse, = , 0. |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | Polyphenol-rich extract of Ocimum gratissimum leaves prevented toxic effects of cyclophosphamide on the kidney function of Wistar rats.. Cyclophosphamide (CP) is one of the potent and low cost chemotherapy used in clinical setting against a variety of tumors. However, its association with nephrotoxicity limits its therapeutic use. Ocimum gratissimum leaf is a medicinal plant with numerous pharmaco… |
Toxicology CRS | grade 4 |
Clinical Primary efficacy | ORR 95% |
Clinical ORR | 95.0% |
Clinical Result source | ClinicalTrials.gov NCT03677141 |
Clinical Data Tier / Score | A · 62 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 9일 (5일 전) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-14 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Cyclophosphamid |
Overview Company | Essen Biotech |
Overview Modality | ANTIBODY |
Overview Target | Stomach Cancer |
Overview Indication | Stomach Cancer; Stomach Cancer Recurrent |
Overview Phase | PHASE_2 |
Overview Status | RECRUITING |
MoA Mechanism | CAR-T therapy induced profound, durable responses in extremely severe patients with seropositive PIRR |
MoA Biomarker | biomarkers |
PK/PD Species | Mouse, = , 0. |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | PK |
Toxicology Species | Mouse, = , 0. |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | Polyphenol-rich extract of Ocimum gratissimum leaves prevented toxic effects of cyclophosphamide on the kidney function of Wistar rats.. Cyclophosphamide (CP) is one of the potent and low cost chemotherapy used in clinical setting against a variety of tumors. However, its association with nephrotoxicity limits its therapeutic use. Ocimum gratissimum leaf is a medicinal plant with numerous pharmaco… |
Toxicology CRS | grade 4 |
Clinical Primary efficacy | ORR 95% |
Clinical ORR | 95.0% |
Clinical Result source | ClinicalTrials.gov NCT03677141 |
Clinical Data Tier / Score | A · 62 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 9일 (5일 전) |
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