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항목
ADCPhase 3
Daunorubicin Hydrochloride (Daunorubicin Hydrochloride)
Alliance for Clinical Trials in On…·Acute Myeloid Leukemia
69 trials·t½ 18.5 h
Overview
Program
Daunorubicin Hydrochloride
Overview
Company
Alliance for Clinical Trials in Oncology
Overview
Modality
ADC
Overview
Target
Acute Myeloid Leukemia
Overview
Indication
B Acute Lymphoblastic Leukemia
Overview
Phase
PHASE_3
Overview
Status
RECRUITING
MoA
Mechanism
targeting IL-4/IL-13 signaling
MoA
Biomarker
biomarker candidate and mechanistic hypothesis for anthracycline responsiveness
PK/PD
Half-life
18.5 h
PK/PD
Species
Rat
PK/PD
Animal (cat.)
Rat
PK/PD
Experiment
PD
Toxicology
Species
Rat
Toxicology
Animal (cat.)
Rat
Toxicology
Major finding
Design and Characterization of Thermosensitive Niosomes as Platforms for Daunorubicin Delivery.. Background/Objectives: The study describes the elaboration and evaluation of thermosensitive niosomes intended for the systemic application of daunorubicin hydrochloride. The attained stimulus sensitivity would determine the release of the chemotherapeutic predominantly at the target site, which ensure…
Toxicology
CRS
Reported
Clinical
OS
5
Clinical
Result source
ClinicalTrials.gov NCT04770272
Clinical
Data Tier / Score
A · 45
Clinical
Program phase
PHASE_3
Clinical
Clinical sync
2026년 7월 9일 (5일 전)