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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
ADCPhase 2
Elacestrant (Elacestrant)
NYU Langone Health·HER2
38 trials·t½ 50 h
Overview
Program
Elacestrant
Overview
Company
NYU Langone Health
Overview
Modality
ADC
Overview
Target
HER2
Overview
Indication
ER Positive, HER2 Positive Breast Cancer
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
MoA
Mechanism
of oral SERDs compared with prior endocrine therapies and evaluates clinical evidence supporting their use across treatment settings in HR+/HER2- breast cancer
MoA
Biomarker
biomarkers and signaling pathways
PK/PD
Half-life
50 h
PK/PD
Species
Rat
PK/PD
Animal (cat.)
Rat, In vitro
PK/PD
Experiment
TGI
Toxicology
Species
Rat
Toxicology
Animal (cat.)
Rat, In vitro
Toxicology
Major finding
A Computational Strategy to Identify Hub Genes in Pathway Analysis of Gamma Tocotrienol-treated MCF-7 Cells and Molecular Docking Study Using Selected Phytochemicals as Therapeutic Agents.. Breast cancer is a highly prevalent malignancy in women, necessitating the discovery of novel therapeutic approaches. Researchers have focused on various medicinal plants for their therapeutic benefits, includi…
Clinical
PFS
3.78
Clinical
OS
NA
Clinical
Result source
ClinicalTrials.gov NCT03778931
Clinical
Data Tier / Score
A · 41
Clinical
Program phase
PHASE_2
Clinical
Clinical sync
2026년 7월 13일 (1일 전)