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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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API CSV22행 · 1개 프로그램

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항목
AntibodyApproved
Filgotinib (Filgotinib)
Lakefront Biotherapeutics NV·Rheumatoid Arthritis
ORR 73%·t½ 23.7 h
Overview
Program
Filgotinib
Overview
Company
Lakefront Biotherapeutics NV
Overview
Modality
ANTIBODY
Overview
Target
Rheumatoid Arthritis
Overview
Indication
Rheumatoid Arthritis
Overview
Phase
APPROVED
Overview
Status
RECRUITING
MoA
Mechanism
targeting non-cytokine pathway
MoA
Biomarker
biomarker development to optimize therapeutic selection and improve long-term outcomes
PK/PD
Half-life
23.7 h
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
Biologic drugs for induction and maintenance of remission in Crohn's disease: a network meta-analysis.. Crohn's disease is an inflammatory bowel disease (IBD) that can extend to any part of the gut. Many people with Crohn's disease fail to reach and maintain remission using conventional therapies. Biologic therapies with different mechanisms have advanced rapidly over recent decades. Comparative d…
Clinical
Primary efficacy
ORR 73%
Clinical
ORR
19%
Clinical
Result source
ClinicalTrials.gov NCT01888874
Clinical
Data Tier / Score
A · 67
Clinical
Program phase
APPROVED
Clinical
Clinical sync
2026년 7월 13일 (1일 전)