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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
CGTPhase 1
Gene Modified T Cells (Gene Modified T Cells)
Calimmune, Inc.·Prostate Cancer
ORR 92.9%
Overview
Program
Gene Modified T Cells
Overview
Company
Calimmune, Inc.
Overview
Modality
CGT
Overview
Target
Prostate Cancer
Overview
Indication
Prostate Cancer
Overview
Phase
PHASE_1
Overview
Status
DISCONTINUED
MoA
Mechanism
targeting multiple tumor antigen to avoid tumor antigen
MoA
Biomarker
biomarkers to optimize selection of patients who most likely would benefit from ACT, using combination therap
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
Ready or not, here they come: a practical guide to adoptive T-cell therapies for solid tumors for medical oncologists.. Adoptive cell therapies (ACTs) include chimeric antigen receptors (CARs), bispecific T-cell engagers (BiTES), tumor-infiltrating lymphocytes, and T-cell receptor (TCR) gene-modified T-cells. ACTs have significantly improved patient outcomes associated with hematologic malignancie…
Toxicology
CRS
Reported
Clinical
Primary efficacy
ORR 92.9%
Clinical
ORR
92.9%
Clinical
Result source
ClinicalTrials.gov NCT03310619
Clinical
Data Tier / Score
A · 37
Clinical
Program phase
PHASE_1
Clinical
Clinical sync
2026년 7월 13일 (1일 전)