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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
ADCPhase 3
HER2-targeted Therapy (HER2-targeted Therapy)
SWOG Cancer Research Network·HER2
ORR 18.75%
Overview
Program
HER2-targeted Therapy
Overview
Company
SWOG Cancer Research Network
Overview
Modality
ADC
Overview
Target
HER2
Overview
Indication
Anatomic Stage IV Breast Cancer AJCC v8; Metastatic HER2-Positive Breast Carcinoma
Overview
Phase
PHASE_3
Overview
Status
RECRUITING
MoA
Mechanism
Targeting HER2-associated antigen
MoA
Biomarker
HER2-low
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
Case Report: Case studies evaluating anti-HER2 therapy as a tumor-agnostic strategy in rare malignancies.. Despite the success of HER2-targeted antibody-drug conjugates (ADCs) in common cancers, there is a lack of real-world evidence regarding their role in rare tumors where ERBB2 gene amplification by next-generation sequencing (NGS) may serve as a more precise driver than traditional protein exp…
Clinical
Primary efficacy
ORR 18.75%
Clinical
ORR
18.75%
Clinical
Result source
ClinicalTrials.gov NCT00622466
Clinical
Data Tier / Score
A · 48
Clinical
Program phase
PHASE_3
Clinical
Clinical sync
2026년 7월 13일 (1일 전)