검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Hyaluronidase (Hyaluronidase) Merck Sharp & Dohme LLC·Diffuse Large B-cell Lymphoma ORR 64.3%·t½ 0.5 h |
|---|---|
Overview Program | Hyaluronidase |
Overview Company | Merck Sharp & Dohme LLC |
Overview Modality | ADC |
Overview Target | Diffuse Large B-cell Lymphoma |
Overview Indication | Diffuse Large B-cell Lymphoma |
Overview Phase | PHASE_2 |
Overview Status | DISCONTINUED |
MoA Mechanism | targeting coagulation and inflammatory pathway |
MoA Biomarker | biomarker-guided approaches |
PK/PD Half-life | 0.5 h |
PK/PD Species | Mouse |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Mouse |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | Kombucha-Mediated Fermentation Enhances Antioxidant, Anti-Inflammatory, Anti-Ageing and Antimicrobial Properties of Fruit Tree Leaf Agro-Waste Extracts from Malus domestica , Prunus armeniaca and Prunus cerasus .. Fruit tree leaves are an abundant agro-waste material with promising yet underexplored biological potential. This study compared the biological activity of aqueous extracts obtained from… |
Clinical Primary efficacy | ORR 64.3% |
Clinical ORR | 64.3% |
Clinical Result source | ClinicalTrials.gov NCT06212752 |
Clinical Data Tier / Score | A · 36 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 13일 (1일 전) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | Hyaluronidase (Hyaluronidase) Merck Sharp & Dohme LLC·Diffuse Large B-cell Lymphoma ORR 64.3%·t½ 0.5 h |
|---|---|
Overview Program | Hyaluronidase |
Overview Company | Merck Sharp & Dohme LLC |
Overview Modality | ADC |
Overview Target | Diffuse Large B-cell Lymphoma |
Overview Indication | Diffuse Large B-cell Lymphoma |
Overview Phase | PHASE_2 |
Overview Status | DISCONTINUED |
MoA Mechanism | targeting coagulation and inflammatory pathway |
MoA Biomarker | biomarker-guided approaches |
PK/PD Half-life | 0.5 h |
PK/PD Species | Mouse |
PK/PD Animal (cat.) | Mouse |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Mouse |
Toxicology Animal (cat.) | Mouse |
Toxicology Major finding | Kombucha-Mediated Fermentation Enhances Antioxidant, Anti-Inflammatory, Anti-Ageing and Antimicrobial Properties of Fruit Tree Leaf Agro-Waste Extracts from Malus domestica , Prunus armeniaca and Prunus cerasus .. Fruit tree leaves are an abundant agro-waste material with promising yet underexplored biological potential. This study compared the biological activity of aqueous extracts obtained from… |
Clinical Primary efficacy | ORR 64.3% |
Clinical ORR | 64.3% |
Clinical Result source | ClinicalTrials.gov NCT06212752 |
Clinical Data Tier / Score | A · 36 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 13일 (1일 전) |
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