검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Metoprolol |
Overview Company | Bristol-Myers Squibb |
Overview Modality | CGT |
Overview Target | Solid Tumor |
Overview Indication | Breast Cancer; Heart Failure |
Overview Phase | PHASE_2 |
Overview Status | ACTIVE |
MoA Biomarker | biomarkers, suggesting that the predominant mechanism of toxic myocardial injury in this context may be elect |
PK/PD Half-life | 4 h |
PK/PD Species | Rat, Human |
PK/PD Animal (cat.) | Human, Rat |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Rat, Human |
Toxicology Animal (cat.) | Human, Rat |
Toxicology Major finding | Sublethal stress from polypharmacy modulates scavenging function and fenestrations in mouse liver sinusoidal endothelial cells.. Polypharmacy, the concurrent use of multiple medications, is increasingly prevalent in older people and is associated with adverse outcomes such as falls, frailty, functional, and cognitive decline, and increased hospitalization and mortality. The liver, as the primary s… |
Clinical Primary efficacy | ORR 62.11% |
Clinical ORR | 62.11% |
Clinical Result source | ClinicalTrials.gov NCT03488719 |
Clinical Data Tier / Score | A · 53 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 12일 (1일 전) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Metoprolol |
Overview Company | Bristol-Myers Squibb |
Overview Modality | CGT |
Overview Target | Solid Tumor |
Overview Indication | Breast Cancer; Heart Failure |
Overview Phase | PHASE_2 |
Overview Status | ACTIVE |
MoA Biomarker | biomarkers, suggesting that the predominant mechanism of toxic myocardial injury in this context may be elect |
PK/PD Half-life | 4 h |
PK/PD Species | Rat, Human |
PK/PD Animal (cat.) | Human, Rat |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Rat, Human |
Toxicology Animal (cat.) | Human, Rat |
Toxicology Major finding | Sublethal stress from polypharmacy modulates scavenging function and fenestrations in mouse liver sinusoidal endothelial cells.. Polypharmacy, the concurrent use of multiple medications, is increasingly prevalent in older people and is associated with adverse outcomes such as falls, frailty, functional, and cognitive decline, and increased hospitalization and mortality. The liver, as the primary s… |
Clinical Primary efficacy | ORR 62.11% |
Clinical ORR | 62.11% |
Clinical Result source | ClinicalTrials.gov NCT03488719 |
Clinical Data Tier / Score | A · 53 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 12일 (1일 전) |
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