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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
CGTPhase 1
NK cell therapy (NK cell therapy)
Royan Institute·Glioma Glioblastoma Multiforme
58 trials
Overview
Program
NK cell therapy
Overview
Company
Royan Institute
Overview
Modality
CGT
Overview
Target
Glioma Glioblastoma Multiforme
Overview
Indication
Glioblastoma Multiform; Recurrent Glioblastoma
Overview
Phase
PHASE_1
Overview
Status
ACTIVE
MoA
Mechanism
targeting and cytotoxicity by coupling NK cells with tumor-specific antibodies targeting antigen
MoA
Biomarker
biomarker of disease biology
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
Safety and feasibility of 5T4 antibody-coupled allogeneic NK cell therapy for solid tumors: a first-in-human phase 1 trial.. Patients with unresectable locally advanced or metastatic solid tumors have limited therapeutic options. Antibody-guided allogeneic natural killer (NK) cell therapy represents a novel immunotherapeutic strategy to enhance tumor targeting and cytotoxicity by coupling NK cells…
Toxicology
CRS
Reported
Clinical
OS
16
Clinical
Result source
ClinicalTrials.gov NCT00787761
Clinical
Data Tier / Score
A · 31
Clinical
Program phase
PHASE_1
Clinical
Clinical sync
2026년 7월 13일 (1일 전)