검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 21일
현재 선택: 2개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | ||
|---|---|---|
Overview Program | Remicade (infliximab) | reduction or discontinuation of Adalimumab |
Overview Company | Janssen | Dan Liang |
Overview Modality | ANTIBODY | ANTIBODY |
Overview Target | Rheumatoid Arthritis | Uveitis |
Overview Indication | Uveitis | Uveitis; Adalimumab |
Overview Phase | PHASE_3 | PHASE_2 |
Overview Status | ACTIVE | ACTIVE |
MoA Mechanism | targeted metabolomics, to delineate microbial and metabolic signatures predictive of IFX induction efficacy and to explore mechanistic pathway | — |
PK/PD Species | Mouse | — |
PK/PD Animal (cat.) | Mouse | — |
PK/PD Experiment | pharmacokinetic | — |
Toxicology Species | Mouse | — |
Toxicology Animal (cat.) | Mouse | — |
Toxicology Major finding | Upadacitinib salvage for refractory immune checkpoint inhibitor colitis complicated by cytomegalovirus infection.. Immune checkpoint inhibitor colitis is a common immune-related adverse event associated with immunotherapy and may be refractory to corticosteroids and biologic therapy. Evidence guiding management beyond anti-tumour necrosis factor and anti-integrin therapy remains limited. We report… | Association of Variants in Candidate Pharmacogenes with Response to Mercaptopurine and Methotrexate in Pediatric Acute Lymphoblastic Leukemia: A Single-Center Experience from Croatia.. Interindividual variability in the efficacy and toxicity of 6-mercaptopurine (6-MP) and methotrexate (MTX) drugs remains a major challenge in the treatment of pediatric acute lymphoblastic leukemia (ALL). Germline v… |
Clinical Data Tier / Score | S · 38 | C · 10 |
Clinical Program phase | PHASE_3 | PHASE_2 |
Clinical Clinical sync | 2026년 7월 12일 (9일 전) | 2026년 5월 22일 (60일 전 · 갱신 권장) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 21일
현재 선택: 2개 · 임상 갱신 필요 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | ||
|---|---|---|
Overview Program | Remicade (infliximab) | reduction or discontinuation of Adalimumab |
Overview Company | Janssen | Dan Liang |
Overview Modality | ANTIBODY | ANTIBODY |
Overview Target | Rheumatoid Arthritis | Uveitis |
Overview Indication | Uveitis | Uveitis; Adalimumab |
Overview Phase | PHASE_3 | PHASE_2 |
Overview Status | ACTIVE | ACTIVE |
MoA Mechanism | targeted metabolomics, to delineate microbial and metabolic signatures predictive of IFX induction efficacy and to explore mechanistic pathway | — |
PK/PD Species | Mouse | — |
PK/PD Animal (cat.) | Mouse | — |
PK/PD Experiment | pharmacokinetic | — |
Toxicology Species | Mouse | — |
Toxicology Animal (cat.) | Mouse | — |
Toxicology Major finding | Upadacitinib salvage for refractory immune checkpoint inhibitor colitis complicated by cytomegalovirus infection.. Immune checkpoint inhibitor colitis is a common immune-related adverse event associated with immunotherapy and may be refractory to corticosteroids and biologic therapy. Evidence guiding management beyond anti-tumour necrosis factor and anti-integrin therapy remains limited. We report… | Association of Variants in Candidate Pharmacogenes with Response to Mercaptopurine and Methotrexate in Pediatric Acute Lymphoblastic Leukemia: A Single-Center Experience from Croatia.. Interindividual variability in the efficacy and toxicity of 6-mercaptopurine (6-MP) and methotrexate (MTX) drugs remains a major challenge in the treatment of pediatric acute lymphoblastic leukemia (ALL). Germline v… |
Clinical Data Tier / Score | S · 38 | C · 10 |
Clinical Program phase | PHASE_3 | PHASE_2 |
Clinical Clinical sync | 2026년 7월 12일 (9일 전) | 2026년 5월 22일 (60일 전 · 갱신 권장) |
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