검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Valacyclovir |
Overview Company | GlaxoSmithKline |
Overview Modality | ANTIBODY |
Overview Target | Metastatic Non-small Cell Lung Cancer |
Overview Indication | Metastatic Non-small Cell Lung Cancer; Metastatic Triple-negative Breast Cancer |
Overview Phase | PHASE_2 |
Overview Status | ACTIVE |
MoA Mechanism | of AXX-18 was found to be similar to that of oleanolic acid, except that AXX-18 could act on both the UL8 and UL52 proteins of the uncoupling helicase-primase enzyme, whereas oleanolic acid could only act on the UL8 pro |
MoA Biomarker | biomarkers for AD, a positive serum antibody test (IgG or IgM) for HSV-1 or HSV-2, and a Mini-Mental State Ex |
PK/PD Half-life | 14 h |
PK/PD Species | Rat |
PK/PD Animal (cat.) | Rat |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Rat |
Toxicology Animal (cat.) | Rat |
Toxicology Major finding | Refractory and/or Resistant Herpes Simplex Virus Mucocutaneous Infections in Adult Transplantation and Cellular Therapy Patients: A Single-Center Experience.. Purpose and methods Refractory and/or resistant herpes simplex virus (R/R HSV) mucocutaneous infections are an emerging challenge in immunocompromised hosts. A single-center retrospective study of R/R HSV mucocutaneous infections in allogene… |
Clinical Primary efficacy | ORR 20% |
Clinical ORR | 20% |
Clinical Result source | ClinicalTrials.gov NCT00492050 |
Clinical Data Tier / Score | A · 38 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 12일 (1일 전) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Valacyclovir |
Overview Company | GlaxoSmithKline |
Overview Modality | ANTIBODY |
Overview Target | Metastatic Non-small Cell Lung Cancer |
Overview Indication | Metastatic Non-small Cell Lung Cancer; Metastatic Triple-negative Breast Cancer |
Overview Phase | PHASE_2 |
Overview Status | ACTIVE |
MoA Mechanism | of AXX-18 was found to be similar to that of oleanolic acid, except that AXX-18 could act on both the UL8 and UL52 proteins of the uncoupling helicase-primase enzyme, whereas oleanolic acid could only act on the UL8 pro |
MoA Biomarker | biomarkers for AD, a positive serum antibody test (IgG or IgM) for HSV-1 or HSV-2, and a Mini-Mental State Ex |
PK/PD Half-life | 14 h |
PK/PD Species | Rat |
PK/PD Animal (cat.) | Rat |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Rat |
Toxicology Animal (cat.) | Rat |
Toxicology Major finding | Refractory and/or Resistant Herpes Simplex Virus Mucocutaneous Infections in Adult Transplantation and Cellular Therapy Patients: A Single-Center Experience.. Purpose and methods Refractory and/or resistant herpes simplex virus (R/R HSV) mucocutaneous infections are an emerging challenge in immunocompromised hosts. A single-center retrospective study of R/R HSV mucocutaneous infections in allogene… |
Clinical Primary efficacy | ORR 20% |
Clinical ORR | 20% |
Clinical Result source | ClinicalTrials.gov NCT00492050 |
Clinical Data Tier / Score | A · 38 |
Clinical Program phase | PHASE_2 |
Clinical Clinical sync | 2026년 7월 12일 (1일 전) |
추천 비교
추천 비교