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API CSV20행 · 1개 프로그램

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항목
AntibodyApproved
XGEVA® (XGEVA®)
Amgen·Giant Cell Tumor of Bone
31 trials
Overview
Program
XGEVA®
Overview
Company
Amgen
Overview
Modality
ANTIBODY
Overview
Target
Giant Cell Tumor of Bone
Overview
Indication
Castration-resistant Prostate Cancer; Metastatic Cancer
Overview
Phase
APPROVED
Overview
Status
RECRUITING
MoA
Mechanism
targets and binds with high affinity and specificity to receptor
MoA
Biomarker
Biomarkers, and Emerging Therapies
PK/PD
Species
Mouse, Rabbit, Comparison of pharmacokinetics, pharmacodynamics, safety
PK/PD
Animal (cat.)
Mouse, In vitro
PK/PD
Experiment
pharmacokinetic
Toxicology
Species
Mouse, Rabbit, Comparison of pharmacokinetics, pharmacodynamics, safety
Toxicology
Animal (cat.)
Mouse, In vitro
Toxicology
Major finding
Comparison of pharmacokinetics, pharmacodynamics, safety, and immunogenicity of a candidate biosimilar INTP23.1 with EU and US‑approved denosumab reference products in healthy adult men.. This Phase 1 study evaluated the pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity, and safety of INTP23.1, a proposed denosumab biosimilar, compared with US- and EU-licensed reference denosumab…
Clinical
OS
NA
Clinical
Result source
ClinicalTrials.gov NCT00556374
Clinical
Data Tier / Score
A · 44
Clinical
Program phase
APPROVED
Clinical
Clinical sync
2026년 7월 13일 (1일 전)