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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
AntibodyApproved
Emicizumab (Emicizumab)
Indiana Hemophilia &Thrombosis Cen…·Factor VIII Deficiency, Congenital
ORR 14.77%
Overview
Program
Emicizumab
Overview
Company
Indiana Hemophilia &Thrombosis Center, Inc.
Overview
Modality
ANTIBODY
Overview
Target
Factor VIII Deficiency, Congenital
Overview
Indication
Haemophilic Pseudotumour
Overview
Phase
APPROVED
Overview
Status
DISCONTINUED
MoA
Mechanism
Targeted rebalancing agents enhance coagulation by attenuating endogenous anticoagulants such as tissue factor pathway
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
PD
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
[Evaluation of the efficacy and safety of reduced-dose emicizumab in infants with severe hemophilia A: a single-center real-world study].. To investigate the efficacy and safety of reduced-dose emicizumab (EMI) prophylaxis in infants under one year of age with severe hemophilia A (HA). Medical records of 11 infants aged ≤12 months with severe HA who received reduced-dose EMI in the Departme…
Clinical
Primary efficacy
ORR 14.77%
Clinical
ORR
14.77%
Clinical
Result source
ClinicalTrials.gov NCT03380780
Clinical
Data Tier / Score
A · 25
Clinical
Program phase
APPROVED
Clinical
Clinical sync
2026년 7월 12일 (1일 전)