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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-13 · 마지막 7월 13일

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항목
AntibodyPhase 2
Immune Checkpoint Inhibitors (Immune Checkpoint Inhibitors)
Compugen Ltd·Hepatocellular Carcinoma
ORR 59%
Overview
Program
Immune Checkpoint Inhibitors
Overview
Company
Compugen Ltd
Overview
Modality
ANTIBODY
Overview
Target
Hepatocellular Carcinoma
Overview
Indication
Biliary Tract Cancer; Immune Checkpoint Inhibitor
Overview
Phase
PHASE_2
Overview
Status
RECRUITING
MoA
Mechanism
target of rapamycin (mTOR) pathway
MoA
Biomarker
biomarkers
PK/PD
Species
Mouse
PK/PD
Animal (cat.)
Mouse
PK/PD
Experiment
Pharmacokinetic
Toxicology
Species
Mouse
Toxicology
Animal (cat.)
Mouse
Toxicology
Major finding
De-escalation of Treatment in Metastatic Renal Cell Carcinoma: Why? How? Who? When?. The therapeutic landscape of metastatic renal cell carcinoma (mRCC) has evolved considerably with the introduction of immune checkpoint inhibitors (ICIs) and VEGFR-targeted therapies, leading to unprecedented improvements in survival. As durable responses and deep remissions become more frequent, the question of h…
Toxicology
CRS
Reported
Clinical
Primary efficacy
ORR 59%
Clinical
ORR
59%
Clinical
Result source
ClinicalTrials.gov NCT03729245
Clinical
Data Tier / Score
A · 55
Clinical
Program phase
PHASE_2
Clinical
Clinical sync
2026년 7월 12일 (2일 전)