검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-14 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Remicade® |
Overview Company | Janssen |
Overview Modality | ANTIBODY |
Overview Target | Ankylosing Spondylitis |
Overview Indication | Crohn's Disease |
Overview Phase | APPROVED |
Overview Status | ACTIVE |
MoA Mechanism | targeted metabolomics, to delineate microbial and metabolic signatures predictive of IFX induction efficacy and to explore mechanistic pathway |
MoA Biomarker | biomarkers and safety profile were noted before and after switch |
PK/PD Species | Mouse, Human |
PK/PD Animal (cat.) | Human, Mouse |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Mouse, Human |
Toxicology Animal (cat.) | Human, Mouse |
Toxicology Major finding | Multiple switches between infliximab originator and biosimilars in pediatric inflammatory bowel disease.. Infliximab (IFX) is highly effective but costly, driving the adoption of biosimilars. Data on switching from originator IFX to biosimilars in pediatric inflammatory bowel disease (IBD) patients remain limited. This study evaluated the safety and efficacy of switching from originator IFX to IFX… |
Clinical Primary efficacy | ORR 56.6% |
Clinical ORR | 17.2% |
Clinical Result source | ClinicalTrials.gov NCT02990806 |
Clinical Data Tier / Score | A · 58 |
Clinical Program phase | APPROVED |
Clinical Clinical sync | 2026년 7월 9일 (5일 전) |
검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-14 · 마지막 7월 13일
현재 선택: 1개
프로그램 상세에서 관심 등록 후 2개 이상 모으면 여기서 한 번에 비교할 수 있습니다.
표가 넓으면 좌우로 스크롤하세요. 핵심 비교 모드에서는 중요 항목만 표시됩니다.
| 항목 | |
|---|---|
Overview Program | Remicade® |
Overview Company | Janssen |
Overview Modality | ANTIBODY |
Overview Target | Ankylosing Spondylitis |
Overview Indication | Crohn's Disease |
Overview Phase | APPROVED |
Overview Status | ACTIVE |
MoA Mechanism | targeted metabolomics, to delineate microbial and metabolic signatures predictive of IFX induction efficacy and to explore mechanistic pathway |
MoA Biomarker | biomarkers and safety profile were noted before and after switch |
PK/PD Species | Mouse, Human |
PK/PD Animal (cat.) | Human, Mouse |
PK/PD Experiment | pharmacokinetic |
Toxicology Species | Mouse, Human |
Toxicology Animal (cat.) | Human, Mouse |
Toxicology Major finding | Multiple switches between infliximab originator and biosimilars in pediatric inflammatory bowel disease.. Infliximab (IFX) is highly effective but costly, driving the adoption of biosimilars. Data on switching from originator IFX to biosimilars in pediatric inflammatory bowel disease (IBD) patients remain limited. This study evaluated the safety and efficacy of switching from originator IFX to IFX… |
Clinical Primary efficacy | ORR 56.6% |
Clinical ORR | 17.2% |
Clinical Result source | ClinicalTrials.gov NCT02990806 |
Clinical Data Tier / Score | A · 58 |
Clinical Program phase | APPROVED |
Clinical Clinical sync | 2026년 7월 9일 (5일 전) |
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