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검색으로 10,000+ 프로그램 중 최대 5개를 골라 PK/PD · 독성 · 임상을 나란히 비교합니다. · 다음 갱신 D-14 · 마지막 7월 13일

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API CSV23행 · 1개 프로그램

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항목
AntibodyPhase 3
Sarilumab (Sarilumab)
Wei-Che Ko·Melanoma
ORR 3.5%·t½ 10 h
Overview
Program
Sarilumab
Overview
Company
Wei-Che Ko
Overview
Modality
ANTIBODY
Overview
Target
Melanoma
Overview
Indication
Skin Inflammation; Allergic Contact Dermatitis
Overview
Phase
PHASE_3
Overview
Status
RECRUITING
MoA
Mechanism
s and infections appeared limited
MoA
Biomarker
biomarker, imaging, or patient reported outcomes were included
PK/PD
Half-life
10 h
PK/PD
Species
Human
PK/PD
Animal (cat.)
Human
PK/PD
Experiment
Pharmacokinetic
Toxicology
Species
Human
Toxicology
Animal (cat.)
Human
Toxicology
Major finding
Comparative effectiveness and safety of sarilumab vs JAK inhibitors in late- and younger-onset rheumatoid arthritis.. Glucocorticoid (GC)- and MTX-sparing strategies are clinically important in RA, yet comparative real-world evidence for sarilumab (SAR) vs Janus kinase inhibitors (JAKi) is limited. Whether treatment effects differ by age at onset-late-onset RA (LORA) vs young-onset RA (YORA)-also …
Toxicology
CRS
Reported
Clinical
Primary efficacy
ORR 3.5%
Clinical
ORR
3.5%
Clinical
Result source
ClinicalTrials.gov NCT01900431
Clinical
Data Tier / Score
A · 41
Clinical
Program phase
PHASE_3
Clinical
Clinical sync
2026년 7월 12일 (1일 전)