Yake Biotechnology Ltd.
CD19/CD22 CAR T-Cells(Yake Biotechnology Ltd.)은 CD19 표적 세포·유전자 치료로, Acute Lymphoblastic Leukemia 영역에서 개발·상용화 중입니다. 작용기전: target antigen loss and expression downregulation highlights the critical need to anticipate antigen. Phase 1 안전성·PK 탐색 단계입니다. ClinicalTrials.gov 기준 54건의 관련 임상이 등록되어 있습니다. 차별점: novel insights into CAR T-cell immunotherapy.
CD19
Acute Lymphoblastic Leukemia
Recruiting
bispecific CD19/CD22 CAR T cells have been explored, limited persisten
lentiviral vector encoding a CD19/CD22 bispecific CAR, and expanded in gas permeable cell
humanized mouse model with a diverse human T-cell receptor (TCR) repertoire, we identified a high-affinity TC
novel insights into CAR T-cell immunotherapy
target antigen loss and expression downregulation highlights the critical need to anticipate antigen
T cells effectively induce cytotoxicity
CD19low
downregulation of CD19 and/or CD22 have compromised their efficacy in relapsing patients
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.
Yake Biotechnology Ltd.
CD19/CD22 CAR T-Cells(Yake Biotechnology Ltd.)은 CD19 표적 세포·유전자 치료로, Acute Lymphoblastic Leukemia 영역에서 개발·상용화 중입니다. 작용기전: target antigen loss and expression downregulation highlights the critical need to anticipate antigen. Phase 1 안전성·PK 탐색 단계입니다. ClinicalTrials.gov 기준 54건의 관련 임상이 등록되어 있습니다. 차별점: novel insights into CAR T-cell immunotherapy.
CD19
Acute Lymphoblastic Leukemia
Recruiting
bispecific CD19/CD22 CAR T cells have been explored, limited persisten
lentiviral vector encoding a CD19/CD22 bispecific CAR, and expanded in gas permeable cell
humanized mouse model with a diverse human T-cell receptor (TCR) repertoire, we identified a high-affinity TC
novel insights into CAR T-cell immunotherapy
target antigen loss and expression downregulation highlights the critical need to anticipate antigen
T cells effectively induce cytotoxicity
CD19low
downregulation of CD19 and/or CD22 have compromised their efficacy in relapsing patients
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.