VEGF trap fusion protein for retinal vascular diseases; long-acting intravitreal anti-VEGF benchmark. 대표 임상 효능: ORR 9% (ClinicalTrials.gov NCT02357342).
VEGF-A / VEGF-B / PIGF
Wet AMD, DME, RVO, diabetic retinopathy
US, EU, JP
Approved
bispecific antibody targeting both VEGF-A and angiopoietin-2, has emer
linker, enabling self-assembly into a well-defined 24-mer nanostructure (≈29&#x
AAV-aflibercept-Fc-YTE (F-CRG-B191): A Gene Therapy for Neovascular Age-Related Mac
unique records
inhibits its phosphorylation at Tyr42, promotes retention of the TGFβ receptor
apoptosis, and VEGF-A levels were evaluated using confocal microscopy, plate reader-based assays, and ELISA techniques
biomarkers can reliably diagnose and monitor PCV, restricting the role of invasive indocyanine green angiogra
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.
VEGF trap fusion protein for retinal vascular diseases; long-acting intravitreal anti-VEGF benchmark. 대표 임상 효능: ORR 9% (ClinicalTrials.gov NCT02357342).
VEGF-A / VEGF-B / PIGF
Wet AMD, DME, RVO, diabetic retinopathy
US, EU, JP
Approved
bispecific antibody targeting both VEGF-A and angiopoietin-2, has emer
linker, enabling self-assembly into a well-defined 24-mer nanostructure (≈29&#x
AAV-aflibercept-Fc-YTE (F-CRG-B191): A Gene Therapy for Neovascular Age-Related Mac
unique records
inhibits its phosphorylation at Tyr42, promotes retention of the TGFβ receptor
apoptosis, and VEGF-A levels were evaluated using confocal microscopy, plate reader-based assays, and ELISA techniques
biomarkers can reliably diagnose and monitor PCV, restricting the role of invasive indocyanine green angiogra
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.