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ADCPhase 1Recruiting

Itraconazole

Eli Lilly

비교

Itraconazole(Eli Lilly and Company)은 Fallopian Tube Cancer 표적 ADC로, Ovarian Neoplasms; Endometrial Neoplasms 영역에서 개발·상용화 중입니다. 작용기전: targeting pathways such as host cell oxidative folding, Na + /K + -ATPase, and MAPK signaling. Phase 1 안전성·PK 탐색 단계입니다. 대표 임상 효능: ORR 10.5% (ClinicalTrials.gov NCT02122770). PK: t½ 17 h. 차별점: uniqueness of our research in terms of the host from which the pathogenic fungi were isolated, further studies are recommended.

출처: ClinicalTrials.gov · PubMed · openFDA최근 동기화됨

개요

임상 2026년 7월 9일 (5일 전)PK/독성 2026년 7월 9일 (5일 전)

Fallopian Tube Cancer

Ovarian Neoplasms; Endometrial Neoplasms

Recruiting

Technology

구조모아 · Exatecan/DXd (TOP1)

NK cells, and immunoglobulin levels

DXd

lipid nanoparticles, and nanostructured lipid carriers for the pulmonary delivery of antifungals f

uniqueness of our research in terms of the host from which the pathogenic fungi were isolated, further studies are recommended

Mechanism of Action

targeting pathways such as host cell oxidative folding, Na + /K + -ATPase, and MAPK signaling

topoisomerase I inhibitor payload (DXd) released from the human epidermal growth factor receptor 2-targeted antibody-drug conjugate (

biomarker in AIDS patients with CM

Resistance to terbinafine is predominantly associated with point mutations in the squalene epoxidase (SQLE) gene

임상시험 & 결과

차트 로드 중…

임상 한눈에 보기

  • 65건의 ClinicalTrials.gov 임상 기록
  • Phase·Status 요약은 enrollment 상위 표본 기준입니다
  • 임상시험 탭에서 enrollment 상위 목록을 불러올 수 있습니다
  • Phase: N/A · Phase 1, Phase 2 · Phase 3 · Phase 1…
  • Status: Completed · Recruiting · Unknown status
  • 주요 endpoint: Parts 1 and 2 - All cohorts except Cohort 1F - Occurrence of treatment emergent adverse events (TEAEs) · treatment related adverse events (TRAEs) · treatment emergent serious adverse events (TESAEs) · and treatment related serious adverse events (TRSAEs) · Parts 1 and 2 - All cohorts except Cohort 1F - Occurrence of dose interruption
  • 등록된 결과: ORR 10.5%
  • 핵심: The primary purpose of this study is to assess the effect of multiple-dose administration of fluconazole on the single-d…

임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.

수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.

참고문헌

자주 묻는 질문

Itraconazole은 어떤 치료제인가요?
Itraconazole(Eli Lilly and Company)은 Fallopian Tube Cancer 표적 ADC로, Ovarian Neoplasms; Endometrial Neoplasms 영역에서 개발·상용화 중입니다. 데이터는 바이오모아 (BioMoa)에서 ClinicalTrials.gov·openFDA·PubMed 기반으로 정리합니다.
Itraconazole의 임상 단계는?
Itraconazole의 현재 단계는 Phase 1입니다.
비슷한 프로그램과 어떻게 비교하나요?
바이오모아 (BioMoa) 비교 페이지에서 PK/PD, 독성, 임상 효능 지표를 나란히 볼 수 있습니다. 동일 타깃·모달리티 프리셋을 함께 참고하세요.