Ofatumumab(Novartis)은 Leukemia 표적 항체로, Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma 영역에서 개발·상용화 중입니다. 작용기전: target cells with low antigen. Phase 3 후기 임상 단계입니다. 대표 임상 효능: ORR 53% (ClinicalTrials.gov NCT01123356). 차별점: novel antibody approaches are needed.
Leukemia
Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma
Recruiting
bispecific T-cell engagers, and chimeric antigen receptor (CAR) T cell
lentiviral vectors for the generation of cell lines that stably produce mAb-SCR-fusion var
humanized anti-CD20 monoclonal antibody, represents a potential alternative, yet its use in children remains
novel antibody approaches are needed
target cells with low antigen
immune-mediated glomerulopathies and potential anti-CD20 therapy alternatives
biomarker-guided retreatment, infection-risk mitigation, and regimen adaptation for non-malignant disease
resistance to these therapies inevitably develops in patients, and thus novel antibody approaches are needed
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.
Ofatumumab(Novartis)은 Leukemia 표적 항체로, Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma 영역에서 개발·상용화 중입니다. 작용기전: target cells with low antigen. Phase 3 후기 임상 단계입니다. 대표 임상 효능: ORR 53% (ClinicalTrials.gov NCT01123356). 차별점: novel antibody approaches are needed.
Leukemia
Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma
Recruiting
bispecific T-cell engagers, and chimeric antigen receptor (CAR) T cell
lentiviral vectors for the generation of cell lines that stably produce mAb-SCR-fusion var
humanized anti-CD20 monoclonal antibody, represents a potential alternative, yet its use in children remains
novel antibody approaches are needed
target cells with low antigen
immune-mediated glomerulopathies and potential anti-CD20 therapy alternatives
biomarker-guided retreatment, infection-risk mitigation, and regimen adaptation for non-malignant disease
resistance to these therapies inevitably develops in patients, and thus novel antibody approaches are needed
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.