Leadiant BiosciencesInc.
Pegaspargase (PEG) Asparaginase(Leadiant Biosciences, Inc.)은 Extranodal NK T Cell Lymphoma 표적 치료제로, Extranodal NK/T-cell Lymphoma 영역에서 개발·상용화 중입니다. 작용기전: inhibits apoptosis via the Akt/Bcl-2/caspase-3 pathway. Phase 2에서 효능·안전성 신호를 검증 중입니다. 대표 임상 효능: ORR 52% (ClinicalTrials.gov NCT03860844). PK: t½ 10 h. 차별점: novel non-PEGylated Fc-fusion G-CSF designed for once-per-cycle administration.
Extranodal NK T Cell Lymphoma
Extranodal NK/T-cell Lymphoma
Recruiting
gene therapy formulations
release
linker to form granular hydrogels
retroviral therapy on HIV reservoir clearance in acute HIV infection: study protocol for a
novel non-PEGylated Fc-fusion G-CSF designed for once-per-cycle administration
inhibits apoptosis via the Akt/Bcl-2/caspase-3 pathway
cytokine release
apoptosis via the Akt/Bcl-2/caspase-3 pathway
biomarker-driven framework, centered on BRCA1 methylation and HIF-1α, along with a three-phase translat
resistance to systemic therapies limiting outcomes
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.
Leadiant BiosciencesInc.
Pegaspargase (PEG) Asparaginase(Leadiant Biosciences, Inc.)은 Extranodal NK T Cell Lymphoma 표적 치료제로, Extranodal NK/T-cell Lymphoma 영역에서 개발·상용화 중입니다. 작용기전: inhibits apoptosis via the Akt/Bcl-2/caspase-3 pathway. Phase 2에서 효능·안전성 신호를 검증 중입니다. 대표 임상 효능: ORR 52% (ClinicalTrials.gov NCT03860844). PK: t½ 10 h. 차별점: novel non-PEGylated Fc-fusion G-CSF designed for once-per-cycle administration.
Extranodal NK T Cell Lymphoma
Extranodal NK/T-cell Lymphoma
Recruiting
gene therapy formulations
release
linker to form granular hydrogels
retroviral therapy on HIV reservoir clearance in acute HIV infection: study protocol for a
novel non-PEGylated Fc-fusion G-CSF designed for once-per-cycle administration
inhibits apoptosis via the Akt/Bcl-2/caspase-3 pathway
cytokine release
apoptosis via the Akt/Bcl-2/caspase-3 pathway
biomarker-driven framework, centered on BRCA1 methylation and HIF-1α, along with a three-phase translat
resistance to systemic therapies limiting outcomes
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.