Pemetrexed/Cisplatin(AstraZeneca)은 Non-small Cell Lung Cancer 표적 ADC로, Non-Small-Cell Lung Carcinoma NSCLC 영역에서 개발·상용화 중입니다. 작용기전: (MOA) of FL496 overlaps with, but is likely beyond the scope of FL118 MOA, which needs further investigation. Phase 3 후기 임상 단계입니다. 대표 임상 효능: ORR 44% (ClinicalTrials.gov NCT03003962). 차별점: novel FL118-derived small molecule (FL496).
Non-small Cell Lung Cancer
Non-Small-Cell Lung Carcinoma NSCLC
Recruiting
CAR-T cell therapy, are being investigated
novel FL118-derived small molecule (FL496)
(MOA) of FL496 overlaps with, but is likely beyond the scope of FL118 MOA, which needs further investigation
T-cell activation
apoptosis of malignant pleural mesothelioma (MPM) cells, and exhibits anti-MPM tumor efficacy strikingly superior to the pemetrex
biomarkers, renal lipid peroxidation, and nitrosative stress compared with pemetrexed or cisplatin alone
resistance to various pharmaceuticals, the relationship between drug concentration and cancer cell death, as well as the fine dynamic
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.
Pemetrexed/Cisplatin(AstraZeneca)은 Non-small Cell Lung Cancer 표적 ADC로, Non-Small-Cell Lung Carcinoma NSCLC 영역에서 개발·상용화 중입니다. 작용기전: (MOA) of FL496 overlaps with, but is likely beyond the scope of FL118 MOA, which needs further investigation. Phase 3 후기 임상 단계입니다. 대표 임상 효능: ORR 44% (ClinicalTrials.gov NCT03003962). 차별점: novel FL118-derived small molecule (FL496).
Non-small Cell Lung Cancer
Non-Small-Cell Lung Carcinoma NSCLC
Recruiting
CAR-T cell therapy, are being investigated
novel FL118-derived small molecule (FL496)
(MOA) of FL496 overlaps with, but is likely beyond the scope of FL118 MOA, which needs further investigation
T-cell activation
apoptosis of malignant pleural mesothelioma (MPM) cells, and exhibits anti-MPM tumor efficacy strikingly superior to the pemetrex
biomarkers, renal lipid peroxidation, and nitrosative stress compared with pemetrexed or cisplatin alone
resistance to various pharmaceuticals, the relationship between drug concentration and cancer cell death, as well as the fine dynamic
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.