Gamma Medica-Ideas
tamoxifen citrate(Gamma Medica-Ideas)은 Breast Cancer 표적 세포·유전자 치료로, Male Breast Cancer; Stage II Breast Cancer 영역에서 개발·상용화 중입니다. 작용기전: target genes in hyaloid endothelial cells, consistent with a role for GPR124 in mediating WNT/β-catenin signaling. Phase 2에서 효능·안전성 신호를 검증 중입니다. 대표 임상 효능: ORR 13% (ClinicalTrials.gov NCT02806544). PK: t½ 7 h. 차별점: novel single MHC class I conditional knockout mice in which H-2K b or H-2D b can be specifically deactivated in TMEM119+ micr.
Breast Cancer
Male Breast Cancer; Stage II Breast Cancer
Active
NK cells (P < 0
lipid nanoparticles as a targeted chemotherapeutic drug
novel single MHC class I conditional knockout mice in which H-2K b or H-2D b can be specifically deactivated in TMEM119+ micr
target genes in hyaloid endothelial cells, consistent with a role for GPR124 in mediating WNT/β-catenin signaling
t cell activation
apoptosis and G0/G1 phase arrest in MDA-MB-231 cells
HER2) negativity and a low
downregulation of several established WNT target genes in hyaloid endothelial cells, consistent with a role for GPR124 in mediating WN
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.
Gamma Medica-Ideas
tamoxifen citrate(Gamma Medica-Ideas)은 Breast Cancer 표적 세포·유전자 치료로, Male Breast Cancer; Stage II Breast Cancer 영역에서 개발·상용화 중입니다. 작용기전: target genes in hyaloid endothelial cells, consistent with a role for GPR124 in mediating WNT/β-catenin signaling. Phase 2에서 효능·안전성 신호를 검증 중입니다. 대표 임상 효능: ORR 13% (ClinicalTrials.gov NCT02806544). PK: t½ 7 h. 차별점: novel single MHC class I conditional knockout mice in which H-2K b or H-2D b can be specifically deactivated in TMEM119+ micr.
Breast Cancer
Male Breast Cancer; Stage II Breast Cancer
Active
NK cells (P < 0
lipid nanoparticles as a targeted chemotherapeutic drug
novel single MHC class I conditional knockout mice in which H-2K b or H-2D b can be specifically deactivated in TMEM119+ micr
target genes in hyaloid endothelial cells, consistent with a role for GPR124 in mediating WNT/β-catenin signaling
t cell activation
apoptosis and G0/G1 phase arrest in MDA-MB-231 cells
HER2) negativity and a low
downregulation of several established WNT target genes in hyaloid endothelial cells, consistent with a role for GPR124 in mediating WN
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.