topotecan hydrochloride(GlaxoSmithKline)은 Fallopian Tube Cancer 표적 세포·유전자 치료로, Fallopian Tube Carcinosarcoma; Fallopian Tube Clear Cell Adenocarcinoma 영역에서 개발·상용화 중입니다. 작용기전: target organs (such as lung and brain) and increase its delivery to the lymphatic system as a major pathway. Phase 2에서 효능·안전성 신호를 검증 중입니다. 대표 임상 효능: ORR 4.86% (ClinicalTrials.gov NCT03061812). PK: t½ 3 h. 차별점: novel, independent poor-prognosis biomarker that orchestrates an inflamed but checkpoint-restricted microenvironment and modu.
Fallopian Tube Cancer
Fallopian Tube Carcinosarcoma; Fallopian Tube Clear Cell Adenocarcinoma
Discontinued
NK cell infusion
SN-38 also augmented IL-10 production signifi
novel, independent poor-prognosis biomarker that orchestrates an inflamed but checkpoint-restricted microenvironment and modu
target organs (such as lung and brain) and increase its delivery to the lymphatic system as a major pathway
macrophages from endotoxemic mice, NC and TOP1 inhibitors significantly enhanced the activation
topoisomerase I-DNA complex to prevent DNA repair and replication, and further induce apoptosis of cancer cells
biomarker for platinum resistance and prognosis in ovarian cancer: a bioinformatics analysis
Downregulation of the Pentose Phosphate Pathway and Prevents Neuronal Apoptosis in Rat Hippocampus Caused by Severe Hypoxia
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.
topotecan hydrochloride(GlaxoSmithKline)은 Fallopian Tube Cancer 표적 세포·유전자 치료로, Fallopian Tube Carcinosarcoma; Fallopian Tube Clear Cell Adenocarcinoma 영역에서 개발·상용화 중입니다. 작용기전: target organs (such as lung and brain) and increase its delivery to the lymphatic system as a major pathway. Phase 2에서 효능·안전성 신호를 검증 중입니다. 대표 임상 효능: ORR 4.86% (ClinicalTrials.gov NCT03061812). PK: t½ 3 h. 차별점: novel, independent poor-prognosis biomarker that orchestrates an inflamed but checkpoint-restricted microenvironment and modu.
Fallopian Tube Cancer
Fallopian Tube Carcinosarcoma; Fallopian Tube Clear Cell Adenocarcinoma
Discontinued
NK cell infusion
SN-38 also augmented IL-10 production signifi
novel, independent poor-prognosis biomarker that orchestrates an inflamed but checkpoint-restricted microenvironment and modu
target organs (such as lung and brain) and increase its delivery to the lymphatic system as a major pathway
macrophages from endotoxemic mice, NC and TOP1 inhibitors significantly enhanced the activation
topoisomerase I-DNA complex to prevent DNA repair and replication, and further induce apoptosis of cancer cells
biomarker for platinum resistance and prognosis in ovarian cancer: a bioinformatics analysis
Downregulation of the Pentose Phosphate Pathway and Prevents Neuronal Apoptosis in Rat Hippocampus Caused by Severe Hypoxia
차트 로드 중…
임상시험이 많습니다. 임상시험 탭에서 Phase/Status 필터·검색을 사용하세요.
수집된 임상 필드(phase, status, endpoint 등) 기반 자동 요약입니다.