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HER2+ 유방암 · HER2

245개 · ADC 1068 · Antibody 5456 · CGT 2744 · 다음 갱신 D-13 · 마지막 7월 13일

인기최근 업데이트큐레이션임상 많은갱신 필요ORR최신Phase 3FDA승인프로그램 245개
ADCBiologicSanofireleasePhase 2

Anthracycline (Anthracycline)

HER2-negative Breast Cancer; Advanced Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 95%임상시험 63상태 RECRUITING
CGTBiologicMerck Sharp & Dohme LLCPhase 3

Recombinant Interferon Alfa-2b (Recombinant Interferon Alfa-2b)

Clinical Stage III Cutaneous Melanoma AJCC v8; Clinical Stage IV Cutaneous Melanoma AJCC v8 · HER2

#HER2#CGT#Phase3#인기#세포유전치료+5
임상시험 63상태 ACTIVE
ADCBiologicAstraZenecaPhase 2

Goserelin (Goserelin)

Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+3
효능 ORR 31%임상시험 62상태 RECRUITING
AntibodyAkesogovitecan), and chimeric an…Phase 2

Ivonescimab (Ivonescimab)

Advanced Microsatellite Stable Colorectal Carcinoma; Metastatic Microsatellite Stable Colorectal Carcinoma · HER2

#HER2#Antibody#Phase2#인기#항체+5
임상시험 62상태 RECRUITING
ADCBiologicSuzhou Suncadia Biopharmaceutic…rezetecanPhase 3

SHR-A1811 (SHR-A1811)

Breast Cancer; HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
임상시험 62상태 RECRUITING
ADCBiologicQuantumLeap Healthcare Collabor…Phase 2

Standard Therapy (Standard Therapy)

Breast Neoplasms; Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 9%임상시험 62상태 RECRUITING
ADCBiologicRelmada Therapeutics, Inc.deruxtecan improved objecti…Phase 2

Control treatment arm (Control treatment arm)

Hormone Receptor(HR)-Positive, Low HER2 Advanced Breast Cancer Patients (HER2 IHC 1+ or 2+ & ISH Negative) · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
임상시험 61상태 RECRUITING
ADCBiologicBioMérieuxderuxtecan plus fluoropyrim…Phase 2

Experimental treatment arm (Experimental treatment arm)

Hormone Receptor(HR)-Positive, Low HER2 Advanced Breast Cancer Patients (HER2 IHC 1+ or 2+ & ISH Negative) · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
임상시험 61상태 RECRUITING
ADCBiologicSWOG Cancer Research NetworkDM1) and/or trastuzumab der…Phase 3

HER2-targeted Therapy (HER2-targeted Therapy)

Anatomic Stage IV Breast Cancer AJCC v8; Metastatic HER2-Positive Breast Carcinoma · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
효능 ORR 18.75%임상시험 59상태 RECRUITING
ADCBiologicRocheDM1 via butelase-1 with ABD…Phase 3

T-DM1 (Trastuzumab emtansine, Trastuzumab emtansine (T-DM1))

Advanced Breast Cancer; Objective Response Rate · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
효능 ORR 69.7%임상시험 59상태 RECRUITING
ADCBiologicJules Bordet InstituteReleasePhase 2

Neratinib (Neratinib)

Breast Cancer; Brain Metastases · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 57.1%임상시험 58상태 RECRUITING
ADCBiologicAssistance Publique - Hôpitaux …Phase 2

Adjuvant Systemic Therapy (Adjuvant Systemic Therapy)

Breast Cancer; HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 10%임상시험 57상태 RECRUITING
ADCBiologicRocheDM1 via butelase-1 with ABD…Phase 2

ado-trastuzumab emtansine (Kadcyla, T-DM1)

Bone Metastases; HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
효능 ORR 69.7%임상시험 57상태 ACTIVE
ADCBiologicRemeGen Co., Ltd.sPhase 2

disitamab vedotin (Disitamab Vedotin, RC48)

Non-Muscle Invasive Bladder Cancer; HER2 · Gastric Cancer/Gastroesophageal Junction

#GastricCancerGastroesophagealJun#ADC#Phase2#인기#항체약물접합체+5
임상시험 56상태 RECRUITING
ADCBiologicSeagen Inc.deruxtecan and tucatinibPhase 1

ONT-380 (Tucatinib, Tucatinib (ONT-380))

HER2 Positive Breast Cancers · HER2

#HER2#ADC#Phase1#인기#항체약물접합체+5
효능 ORR 100%임상시험 54상태 ACTIVE
ADCBiologicQuantumLeap Healthcare Collabor…Phase 2

ABT-888 (ABT-888)

Breast Neoplasms; Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+4
효능 ORR 74.1%임상시험 53상태 RECRUITING
ADCBiologicJiangsu HengRui Medicine Co., L…Phase 2

Famitinib (Famitinib)

Advanced Breast Cancer; Metastatic Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+5
임상시험 53상태 RECRUITING
ADCBiologicFudan UniversityderuxtecanPhase 2

Dalpiciclib (Dalpiciclib)

HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+4
임상시험 52상태 RECRUITING
ADCBiologicSWOG Cancer Research Networkderuxtecan (T-DXd) and tyro…Phase 3

Cyclin-Dependent Kinase 4 Inhibitor (Cyclin-Dependent Kinase 4 Inhibitor)

Anatomic Stage IV Breast Cancer AJCC v8; Metastatic HER2-Positive Breast Carcinoma · HER2

#HER2#ADC#Phase3#인기#항체약물접합체+5
효능 ORR 57.98%임상시험 50상태 RECRUITING
ADCBiologicHoffmann-La RochePhase 2

Entinostat (Entinostat)

Breast Neoplasms · HER2

#HER2#ADC#Phase2#인기#항체약물접합체+4
효능 ORR 22.2%임상시험 50상태 DISCONTINUED

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