HER2+ 유방암

ADCBiologicstaleCelldex TherapeuticsPreclinical

임상시험 9상태 RECRUITING

glembatumumab vedotin (glembatumumab vedotin)

Metastatic gpNMB Expressing Triple Negative Breast Cancer · Melanoma

#Melanoma#ADC#Preclinical#항체약물접합체#antibody-drug-conjugate+2

효능 ORR 21%임상시험 9상태 ACTIVE

ADCBiologicstaleShanghai Henlius BiotechPhase 2

HLX22 (HLX22)

HER2-low Hormone Receptor Positive Breast Cancer · HER2

#HER2#ADC#Phase2#항체약물접합체#antibody-drug-conjugate+2

임상시험 7상태 RECRUITING

ADCBiologicstaleQuantumLeap Healthcare Collabor…Phase 2

[vic-]trastuzumab duocarmazine (SYD985, SYD985 ([vic-]trastuzumab duocarmazine))

Breast Neoplasms; Breast Cancer · HER2

ADCBiologicstaleQuantumLeap Healthcare Collabor…Phase 1

효능 ORR 27.8%임상시험 7상태 RECRUITING

trastuzumab (Herceptin, SYD985, Vic-trastuzumab duocarmazine, Vic-trastuzumab duocarmazine (SYD985) + paclitaxel)

HER2-positive Breast Cancer; HER2 Low · HER2

#HER2#ADC#Phase1#항체약물접합체#antibody-drug-conjugate+3

효능 ORR 27.8%임상시험 7상태 DISCONTINUED

ADCBiologicstaleHoffmann-La RochePhase 2

Atirmociclib (Atirmociclib)

Metastatic Breast Cancer · Metastatic Breast Cancer

#MetastaticBreastCancer#ADC#Phase2#항체약물접합체#antibody-drug-conjugate+1

ADCBiologicstaleRemeGenPhase 2

disitamab vedotin (Disitamab Vedotin, RC48, Disitamab Vedotin Plus Cadonilimab)

Bile Duct Adenocarcinoma Non-Resectable; HER2 Gene Mutation · HER2

ADCBiologicstaleSenhwa Biosciences, Inc.Phase 1

임상시험 6상태 ACTIVE

Pidnarulex (Pidnarulex)

Anatomic Stage III Breast Cancer AJCC v8; Anatomic Stage IV Breast Cancer AJCC v8 · HER2

#HER2#ADC#Phase1#항체약물접합체#antibody-drug-conjugate+3

ADCBiologicstaleAstraZenecaPreclinical

TDxd (TDxd)

Breast Cancer · Breast Cancer

#BreastCancer#ADC#Preclinical#항체약물접합체#antibody-drug-conjugate+1

ADCBiologicstaleNeogap Therapeutics ABPhase 1

LNL (Tumor-draining lymph node-derived lymphocyte, Tumor-draining lymph node-derived lymphocyte (LNL))

Breast Neoplasms · Breast Neoplasms

#BreastNeoplasms#ADC#Phase1#항체약물접합체#antibody-drug-conjugate+1

ADCBiologicstaleSichuan Kelun-Biotech Biopharma…Phase 3

A166 (A166)

HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase3#항체약물접합체#antibody-drug-conjugate+2

ADCBiologicstaleDualityBio Inc.Phase 3

DB-1303/BNT323 (DB-1303/BNT323)

HER2-positive Breast Cancer · HER2

#HER2#ADC#Phase3#항체약물접합체#antibody-drug-conjugate+2

ADCBiologicstaleRayzeBio, Inc.Phase 2

RYZ101 (RYZ101)

Metastatic Breast Cancer; HER2-negative Breast Cancer · HER2

ADCBiologicstaleQuantumLeap Healthcare Collabor…Phase 2

SGN-LIV1A (SGN-LIV1A)

Breast Neoplasms; Breast Cancer · HER2

ADCBiologicstaleQuantumLeap Healthcare Collabor…Phase 2

효능 ORR 34%임상시험 5상태 RECRUITING

Talazoparib plus Irinotecan (Talazoparib plus Irinotecan)

Breast Neoplasms; Breast Cancer · HER2

ADCBiologicstaleRochePhase 2

효능 ORR 0.0%임상시험 5상태 RECRUITING

trastuzumab (Herceptin, Trastuzumab emtansine [Kadcyla])

Breast Cancer · Metastatic Breast Cancer

#MetastaticBreastCancer#ADC#Phase2#항체약물접합체#antibody-drug-conjugate+2

효능 ORR 9.7%임상시험 5상태 ACTIVE

ADCBiologicstaleHoffmann-La RochePhase 2

ZN-A-1041 (ZN-A-1041)

Advanced Solid Tumors; HER2-positive Breast Cancer · HER2

ADCBiologicstaleSeagen Inc.Phase 2

ladiratuzumab vedotin (ladiratuzumab vedotin)

HER2 Positive Breast Neoplasms; Hormone Receptor Positive Breast Neoplasms · HER2

ADCBiologicstaleArtiva Biotherapeutics, Inc.Phase 2

효능 ORR 34%임상시험 5상태 ACTIVE

AB-201 (AB-201)

Breast Cancer; Gastric Cancer · Breast Cancer

#BreastCancer#ADC#Phase2#항체약물접합체#antibody-drug-conjugate+2

임상시험 4상태 DISCONTINUED

ADCBiologicstaleQuantumLeap Healthcare Collabor…Phase 2

Amcenestrant + Letrozole (Amcenestrant + Letrozole)

Breast Neoplasms; Breast Cancer · HER2