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고지혈증 · LDL

14개 · ADC 1048 · Antibody 5323 · CGT 2737 · 다음 갱신 D-14 · 마지막 7월 21일

인기최근 업데이트큐레이션임상 많은갱신 필요ORR최신Phase 3FDA승인프로그램 14개
AntibodySHOTFDACuratedFDABiologicNovartisApproved

inclisiran (Leqvio, KJX839, ALN-PCS)

Hyperlipidemia, ASCVD, HeFH (LDL-C lowering) · PCSK9 (siRNA)

#PCSK9siRNA#Antibody#Approved#FDA승인#바이오모아추천+5
효능 LDL-C ↓50%임상시험 52상태 APPROVED
AntibodySHOTFDACuratedFDABiologicAmgenApproved

evolocumab (Repatha, AMG-145)

Hyperlipidemia, ASCVD risk reduction, HeFH, HoFH · PCSK9

#PCSK9#Antibody#Approved#FDA승인#바이오모아추천+5
효능 LDL-C ↓59%임상시험 51상태 APPROVED
AntibodySHOTFDACuratedFDABiologicSanofiApproved

alirocumab (Praluent, REGN727, SAR236553)

Hyperlipidemia, ASCVD, HeFH · PCSK9

#PCSK9#Antibody#Approved#FDA승인#바이오모아추천+5
효능 LDL-C ↓58%임상시험 45상태 APPROVED
AntibodyAmgenPhase 2

Evolocumab (Evolocumab)

Atherosclerotic Cardiovascular Disease; Symptomatic Atherosclerosis · Primary Hyperlipidemia and Mixed Dyslipi

#PrimaryHyperlipidemiaandMixedDys#Antibody#Phase2#인기#항체+5
효능 ORR 33.3%임상시험 52상태 ACTIVE
CGTBiologicIncyte CorporationPhase 2

pentostatin (pentostatin)

Chronic Myeloproliferative Disorders; Leukemia · Chronic Myeloproliferative Disorders

#ChronicMyeloproliferativeDisorde#CGT#Phase2#세포유전치료#CAR-T+4
효능 ORR 96%임상시험 45상태 DISCONTINUED
CGTAAVBiologicstaleREGENXBIO Inc.Phase 2

AAV directed hLDLR gene therapy (AAV directed hLDLR gene therapy)

Homozygous Familial Hypercholesterolemia (HoFH) · Homozygous Familial Hypercholesterolemia

#HomozygousFamilialHypercholester#CGT#Phase2#세포유전치료#CAR-T+2
임상시험 1상태 DISCONTINUED
CGTAAVBiologicstaleUnlimited Biotechnology LLCPhase 2

AAV9-Follistatin gene therapy (AAV9-Follistatin gene therapy)

Age-related Muscle Decline · Age-related Muscle Decline

#Age-relatedMuscleDecline#CGT#Phase2#세포유전치료#CAR-T+2
임상시험 1상태 RECRUITING
AntibodystaleSanofiPhase 2

Alirocumab (Alirocumab)

Hypercholesterolemia · Hypercholesterolemia

#Hypercholesterolemia#Antibody#Phase2#항체#면역항체+2
임상시험 1상태 ACTIVE
AntibodystaleUniversity of California, San F…Phase 3

Bococizumab (Bococizumab)

Dyslipidemia; Cardiovascular Disease · Dyslipidemia

#Dyslipidemia#Antibody#Phase3#항체#면역항체+3
임상시험 1상태 DISCONTINUED
AntibodystaleHeidelberg UniversityPhase 2

Cyclophosphamide, Pentostatin, Rituximab (Cyclophosphamide, Pentostatin, Rituximab)

Immunocytoma/Morbus Waldenström; B-Cell Non-Hodgkin's Lymphoma · Immunocytoma/Morbus Waldenström

#ImmunocytomaMorbusWaldenstrm#Antibody#Phase2#항체#면역항체+5
임상시험 1상태 ACTIVE
CGTBiologicstaleMinicirclePhase 1

Follistatin and klotho gene therapy (Follistatin and klotho gene therapy)

Healthy Adults · Healthy Adults

#HealthyAdults#CGT#Phase1#세포유전치료#CAR-T+2
임상시험 1상태 RECRUITING
ADCBiologicstaleThe First Affiliated Hospital o…Phase 1

Monomethyl Auristatin E (MMAE, Monomethyl Auristatin E, Monomethyl Auristatin E (MMAE) / autologous neutrophil biological agents)

Unresectable Pancreatic Cancer · Unresectable Pancreatic Cancer

#UnresectablePancreaticCancer#ADC#Phase1#항체약물접합체#antibody-drug-conjugate+1
임상시험 1상태 RECRUITING
AntibodystaleDaping Hospital and the Researc…Phase 2

PCSK9 Inhibitor (Tolecizumab, Tolecizumab (PCSK9 Inhibitor))

Colon Adenocarcinoma · Colon Adenocarcinoma

#ColonAdenocarcinoma#Antibody#Phase2#항체#면역항체+2
임상시험 1상태 RECRUITING
AntibodystaleEli LillyPhase 2

cetuximab/irinotecan/simvastatin (cetuximab/irinotecan/simvastatin)

Metastatic Colorectal Cancer · Metastatic Colorectal Cancer

#MetastaticColorectalCancer#Antibody#Phase2#항체#면역항체+2
임상시험 1상태 ACTIVE